New Master’s thesis: Lena Lenkeit on “Design, development, and experimental verification of a framework for fully-differentiable, gradient-based optimal control of biological systems”

Lena Lenkeit defended her Master’s thesis titled “Design, development, and experimental verification of a framework for fully-differentiable, gradient-based optimal control of biological systems” on 23. October 2023.

This work was done in collaboration with Dr. Dr. Stefan Kallenberger who is also based at the BioQuant.

New Master and Bachelor theses: Emma Kray finished her Bachelor’s thesis and Pascal Lukas defended his Master’s thesis

Emma Kray finished her Bachelor’s thesis titled “A model-based investigation of immune system composition upon vaccinations against influenza” in August.

Pascal Lukas defended his Master’s thesis on “Analyzing and modeling the spatio-temporal dynamics of the interferon response to Dengue virus infection” on 29. September 2023.

Both projects were done in collaboration with the group of Prof. Dr. Frederik Graw at the FAU Erlangen.

30th International Dynamics & Evolution of Human Viruses conference

The 30th International Dynamics & Evolution of Human Viruses conference is taking place from April 19 to 22, 2023 at the German Cancer Research Center (DKFZ) and the Marriott in Heidelberg.

This meeting series was designed to promote discussion between specialists in quantitative and computational approaches in two areas in the field of virology where these are particularly important:

  1. Modeling of viral and cellular dynamics 
  2. Viral evolution and population genetics

We co-organised this meeting together with Frederik Graw, Emma Hodcroft, Denise Kühnert, Richard Neher. Organising institutions are the BioQuant / Heidelberg University and the School of Medicine at UC San Diego.

We provided travel grants for exceptional young researchers from abroad.

You can find more information at the conference webpage.

New Master: Johanna Daas defends her Master’s Thesis

Johanna Daas successfully defended her Master’s thesis titled “Model workflows with the COPASI R Connector (CoRC)” on 10th June 2022.

Congratulations, Johanna!

PS It should be mentioned that Johanna had already published an article as first author in Mathematical Biosciences during her Master’s project:
J.CJ. Daas, J.D Förster and J. Pahle (2022)
Dynamic Publication Media with the COPASI R Connector (CoRC).
Mathematical Biosciences, doi:10.1016/j.mbs.2022.108822 (open access)

New publication on creating Dynamic Publication Media with the COPASI R Connector (CoRC) in Mathematical Biosciences

Mathematical Biosciences accepted our new manuscript, titled “Dynamic Publication Media with the COPASI R Connector (CoRC)” for publication in their special issue “Dynamic Publication Media in Mathematical Biology”.

Dynamic publication media are becoming a popular tool for authors to effectively compose and publish their work. In this article we show how dynamic publication media and the COPASI R Connector (CoRC) can be combined in a natural and synergistic way to communicate (biochemical) models.

For further information please have a look at:
J.CJ. Daas, J.D Förster and J. Pahle (2022)
Dynamic Publication Media with the COPASI R Connector (CoRC).
Mathematical Biosciences, doi:10.1016/j.mbs.2022.108822 (open access)

New publication on our COPASI R Connector (CoRC) software appeared in Bioinformatics

We published an application note in Bioinformatics describing the COPASI R Connector (CoRC), our high-level application programming interface (API) that allows users to access COPASI’s (www.copasi.org) simulation and analysis capabilities from the R programming environment.

For further information please see:
J. Förster, F.T. Bergmann and J. Pahle (2021)
CoRC – the COPASI R Connector.
Bioinformatics, doi:10.1093/bioinformatics/btab033